Based on the roadmap, the small grants program will be the engine to expand basic science research, drug repurposing and the development of novel therapeutics, and the exploration of curative therapies across avenues of gene therapy, ASOs and RNA strategies, among others. Sparking new lines of inquiry will be essential to accelerating the path to a cure, reducing risk across therapeutic options, and enabling treatment options for all people affected by CASK gene disorders regardless of the type of mutation. The program will be useful for junior faculty in the early stages of their careers, established investigators in other areas of research who wish to pursue CASK research, or investigators working on CASK who are seeking funding to support pilot studies in new areas of research. All projects supported through the small grants program must focus on translational research – taking research from the lab and applying it to methods that will directly benefit people affected by CASK - or basic research for critical unanswered questions as defined by Project CASK.